American Cancer Society: âOvarian Cancer Stages,â âRadiation Therapy for Ovarian Cancer,â âSurgery for Ovarian Cancer,â âSurvival Rates for Ovarian Cancer,â âTreatment for Stromal Tumors of the Ovary, by Stage,âÂ âTreatment of Invasive Epithelial Ovarian Cancers, by Stage.â, National Cancer Institute: âDysgerminoma,â âOvarian Germ Cell Tumors Treatment (PDQÂ®)âPatient Version,â âstage IV ovarian epithelial, fallopian tube, and primary peritoneal cancer.â, Ovarian Cancer Research Alliance: âRecurrence.â. Median overall survival was 11.4 months versus 7.2 months, respectively (HR 0.56, 95% CI 0.35-0.91, P=0.017). Stromal tumors: For this cancer type, your doctor will remove the ovary along with the tumor. Youâll get chemotherapy afterward. 34cm of total tumors. You canât predict what will happen to you based on that percentage. 5th ed. But since the studies so far show that maintenance therapy does not necessarily help a woman live longer and may cause more side effects, this is still being studied in clinical trials. A CT scan, PET-CT scan, or MRI might also be done. The smaller the remaining tumor, the better the outlook will be. After surgery, chemo is recommended for at least 6 cycles. If you have other types of germ cell tumors, youâll get chemotherapy before and/or after surgery. The American Cancer Society couldn’t do what we do without the support of our partners. We couldn’t do what we do without our volunteers and donors. Those are âpalliativeâ and donât try to beat the cancer. In addition, some women benefit from hormonal treatment with drugs like anastrozole, letrozole, or tamoxifen. Until we do, we’ll be funding and conducting research, sharing expert information, supporting patients, and spreading the word about prevention. Alternative treatments are used instead of a doctor’s medical treatment. Sometimes you will be recommended to have chemotherapy to shrink the cancer before surgery, followed by another course after the operation. Stage IV ovarian cancer is when the cancer that started in your ovaries or fallopian tubes has spread to other areas of your body. The American Cancer Society is a qualified 501(c)(3) tax-exempt organization. Most often the uterus, both fallopian tubes, and both ovaries are removed (a hysterectomy with bilateral salpingo-oophorectomy). With stage IV ovarian cancer, that chance is 90% to 95%. Stage 4 ovarian cancer is classed as advanced (metastatic) cancer. Whether you want to learn about treatment options, get advice on coping with side effects, or have questions about health insurance, we’re here to help. I'm new to this board as my wife was recently diagnosed with stage IV ovarian cancer. If your ovarian cancer comes back. Stage II fallopian tube and primary peritoneal cancers are also treated with surgery for staging and debulking, followed by chemo. Diagnosed with Stage IIIb endometrial cancer. Treatment with targeted drugs might also be helpful. 3. Sometimes, more surgery is recommended. We’ve invested more than $4.9 billion in cancer research since 1946, all to find more – and better – treatments, uncover factors that may cause cancer, and improve cancer patients’ quality of life. Then you have surgery and more chemotherapy. These cancers are very hard to cure with current treatments, but they can still be treated. Cancer recurrence in September and have started dioxal for now stage 4 and will probably add another drug soon. The type of tumor you have determines what surgery you get and the treatment before and after. For grade 1 (also called low grade) tumors, most women don't need any treatment after surgery. Clinical Oncology. Most people get chemotherapy after surgery. This is called obstruction, and can cause abdominal pain, nausea, and vomiting. A procedure called debulking cytoreductive surgery is used to treat stage 4 ovarian cancer. Advanced epithelial ovarian cancer often comes back months or years after the initial treatment. There are many different chemo drugs that can be used to treat ovarian cancer, so some women may receive several different chemo regimens over several years. What patients and caregivers need to know about cancer, coronavirus, and COVID-19. This type of treatment is called palliative. Giving carboplatin with another drug is also an option. Another option is to treat with chemo first. I am also BRAC I positive. Most often, 3 cycles of chemo are given before surgery, with at least 3 more after surgery (for a total of at least 6 cycles). The combination used most often is carboplatin (or cisplatin) and a taxane, such as paclitaxel (Taxol), given IV (into a vein) for 6 cycles. Ovarian cancer is known to have the highest mortality rate in women as compared to any other cancer of the reproductive system. 10th ed. Ask your cancer care team for information about suitable clinical trials for your type of cancer. Cancer had spread to my lymphatic system. The goals of treatment are to help patients feel better and live longer.Stage IV can be treated like stage III, with surgery to remove the tumor and debulk the cancer, followed by chemo (and possibly the targeted drug bevacizumab [Avastin]). Early-stage ovarian cancer, in which the disease is confi… Home > ; Treatment Options Once a diagnosis of ovarian cancer is made, there are different types of treatment. Cancer.org is provided courtesy of the Leo and Gloria Rosen family. If the patient’s general condition is good, no ascites, limited peritoneal disease on CT scan, surgery followed by chemotherapy is also the option. The goal is to leave behind no visible tumor or no tumor larger than 1 cm. Persistent tumors are those that never went away completely after treatment. Philadelphia, PA: Elsevier; 2014: 1592. The combination of carboplatin and paclitaxel is used most often. In this, special anti-cancer drugs are used to attack the cancerous cells. Ovarian cancer has a few different stages. Treatment Options. Stage IV cancer Stage IV cancer, also known as stage 4 cancer, is a serious disease that requires immediate expert care. After surgery, chemo is recommended, usually with 3 to 6 cycles of treatment with carboplatin and paclitaxel. The first step in treating most stages of ovarian cancer is surgery to remove and stage the cancer. Your response to cancer therapy and chances for a cure depend on the type and the staging of ovarian cancer at the time of diagnosis.. Invasive epithelial ovarian cancer: Your doctor treats stage IV of this type of cancer by removing as much of the tumor as they can see. For women who are not healthy enough to have full staging and debulking surgery, chemo might be given as the first treatment. In this stage, the most effective way of treatment is the first chemotherapy then surgery. Stage 4 is the most advanced and last stage of ovarian cancer. Basic Information About Ovarian Cancer… Thank you for sharing your story. For stage II (including IIA and IIB) cancers, treatment starts with surgery for staging and debulking. This is usually only done if you are well enough to get additional treatments (like chemo) after surgery. The longer it takes for the cancer to come back after treatment, the better the chance that additional chemo will work. Stage 4 ovarian cancer is not curable 3. That means they could take out your ovaries, fallopian tubes, uterus, and some tissue from your abdomen. Stages IA and IB (T1a or T1b, N0, M0): The treatment after surgery depends on the way the cancer cells looks in the lab (called the tumor grade). Centers for Disease Control and Prevention. Imaging tests. Your doctor knows your condition and will help you make the best decisions for your situation. Ovarian cancer can also block the intestinal tract. There are several procedures that might be done, depending on the type of obstruction and your overall health: The American Cancer Society medical and editorial content team. Treating Stage III Ovarian Cancer Most often, your doctor does surgery to remove the cancer. All rights reserved. What does it take to outsmart cancer? 2. The five-year survival rate of stage 1 ovarian cancer is 90%, meaning that about 9 out of 10 patients will still be alive five years after their diagnosis. For grade 3 (high grade) tumors, the treatment usually includes the same chemotherapy that is given for grade 2 Stage IA and IB cancers. Our team of expert journalists brings you all angles of the cancer story – from breaking news and survivor stories to in-depth insights into cutting-edge research. Cancer is called recurrent when it come backs after treatment. They also take out your uterus (a procedure known as a hysterectomy), along with both ovaries and fallopian tubes (a surgery known as a bilateral salpingo-oophorectomy. tumor on outer rectum. Women who want to be able to have children after treatment might be given the option of having an initial surgery that removes only the ovary containing the cancer along with the fallopian tube on the same side. Often, however, the cancer has grown so much in the abdomen that surgery to unblock the intestine doesn't work. While there are other factors of the disease to consider, the ovarian cancer stages are the most useful information to have when learning about a prognosis. The treatment of ovarian cancer is based on the stage of the disease which is a reflection of the extent or spread of the cancer to other parts of the body. At this late stage, ovarian cancer is more difficult to treat. Had surgery September 3 started chemo December 14th. I had Stage IIIC in 2011. Treatment with bevacizumab (Avastin) may also help slow fluid buildup. The doctor also visually examines your external genitalia, vagina and cervix. The aim of treatment is to control the cancer for as long as possible and to help you feel better and live longer. Often, however, their effects are temporary, and the cancer returns or persists. (If it is, it’s typically continued alone after chemo for up to about a year.). For some women, surgery can be done to relieve intestinal obstruction. We can even find you a free ride to treatment or a free place to stay when treatment is far from home. The main treatment is chemotherapy if your cancer comes back. Most often, 3 cycles of chemo are given before surgery, with at least 3 more after surgery. I was diagnosed with stage 3C ovarian cancer November 2016 required surgery and bowel resection. Many things factor into how long you live after a cancer diagnosis. In: DeVita VT, Hellman S, Rosenberg SA, eds. © 2021 American Cancer Society, Inc. All rights reserved. (See Surgery for Ovarian Cancer.) Cytoreductive surgery is beneficial because it reduces the number of cancer cells that ultimately need to be destroyed by chemotherapy and therefore, decreases the likelihood of the cancer developing resistance to chemotherapy. Youâll then get chemotherapy. Stage IV cancer is categorized as distant, meaning itâs spread to areas of your body that arenât close to where it began. Ch 89 – Cancers Arising in the Ovary. The goals of treatment are to help patients feel better and live longer. Recurrence can be local (in or near the same place it started) or distant (spread to organs like the lungs or bone). (If bevacizumab is given, it might be continued alone after chemo or with olaparib.). The main treatments are surgery and chemotherapy. But finally getting it and oncologist is encouraging. Stage IV can be treated like stage III, with surgery to remove the tumor and debulk the cancer, followed by chemo (and possibly the targeted drug bevacizumab [Avastin]). Around two in ten women with advanced-stage ovarian cancer are effectively cured and survive at least 12 years after the treatment as per the research. Sometimes pieces of other organs (like the bladder or liver) may also have to be removed to take out the cancer. Most women with recurrent or persistent ovarian cancer are treated with some form of chemo. Another option is to give intra-abdominal (intraperitoneal or IP) chemo along with intravenous (IV) chemo, after surgery. For example, bevacizumab (Avastin) may be given with chemo. A 5-year relative survival rate tells you how likely it is that people with the same cancer type and stage as you are alive at least 5 years after diagnosis compared to people without that cancer. When this goal is reached, the cancer is said to have been optimally debulked. The chemotherapy is the first line mode of treatment for stage four ovarian cancer patients. This is called ascites. Accessed February 5, 2018, from https://www.nccn.org/professionals/physician_gls/pdf/ovarian.pdf. They could also do another surgery, called a second-look laparotomy, after the first one to see if any cancer remains. Ovarian Epithelial, Fallopian Tube, and Primary Peritoneal Cancer Treatment (PDQ®) — Patient Version. Debulking is also done as needed. From basic information about cancer and its causes to in-depth information on specific cancer types – including risk factors, early detection, diagnosis, and treatment options – you’ll find it here. Another option is to inject chemo directly into the abdomen to slow the buildup of fluid. Oncologist angry that surgeon waited so long to ok chemo. Or you start with chemotherapy to make the tumors smaller. National Cancer Institute. It is aimed at killing any cancer cells that were left behind after treatment but are too small to be seen on tests. The goal of maintenance therapy is to keep the cancer from coming back after platinum chemotherapy. In: Abeloff MD, Armitage JO, Lichter AS, Niederhuber JE, Kastan MB, McKenna WG, eds. Thought it was stage 4, but oncologist said it was stage 3 bordering on 4. This includes a hysterectomy and bilateral salpingo-oophorectomy. During a pelvic exam, your doctor inserts gloved fingers into your vagina and simultaneously presses a hand on your abdomen in order to feel (palpate) your pelvic organs. After the skin is numbed, a needle is used to withdraw the fluid, often several quarts, into a bottle. For reprint requests, please see our Content Usage Policy. Cancer: Principles and Practice of Oncology. Someone who didn't initially receive chemo can be treated with the same drugs that are used for newly diagnosed cancer − usually carboplatin and paclitaxel. Dealing with an intestinal blockage can be difficult. Your doctor may also follow up with radiation to kill any cancer cells the surgery missed. Stage IC (T1c, N0, M0): Standard surgery to remove the cancer is still the first treatment. Survival rate of stage 4 ovarian cancer … Pelvic exam. Theyâll also remove other tissue if the cancer has spread. Which chemo drugs are used depends on what was used the first time and how well it worked (how long the cancer stayed away). Ovarian cancer. The doctor also checks for cancer in other organs and might remove sections of them to get rid of tumors. The aim of treatment is to cure the cancer, if possible. The 5-year relative survival rates for standard types of ovarian cancer tumors are: No matter what stage your cancer diagnosis is, there is always a chance that it can return. MDA did my initial treatment. During cytoreductive surgery, physicians attempt to remove as much of the ovarian cancer as possible. Sometimes a catheter (a thin flexible tube) is placed into the abdomen and left there so that fluid can be removed as often as is needed without using a needle. Complementary methods refer to treatments that are used along with your regular medical care. You can also talk to your doctor about only receiving treatments that help your symptoms. Learn more about these partnerships and how you too can join us in our mission to save lives, celebrate lives, and lead the fight for a world without cancer. These methods can include vitamins, herbs, and special diets, or other methods such as acupuncture or massage, to name a few. Because fallopian tube and primary peritoneal cancers have the same staging system as ovarian cancers they are included in this section. All so you can live longer — and better. Ovarian cancer is uncommonly discovered at stage 1. Some people can be treated for stage 4 ovarian cancer with abdominal surgery that aims to remove as much of the cancer as possible, followed by chemotherapy. This … Doctors may place a tube through the skin and into the stomach to allow the stomach juices to drain, so that the digestive tract isn’t completely blocked. Stage 4 cancer life expectancy without treatment (lung cancer, liver, ovarian, esophageal, bone, stomach, breast cancer, pancreatic) without treatment or with treatment and information about prostate cancer life expectancy.Stage 4 of cancer is a condition in which cancer has spread (metastatic) from its original place to other organs in the body. Hello: I was just diagnosed with Stage IV Ovarian cancer. The treatment after surgery depends on the sub-stage of the cancer. Maintenance therapy: If the cancer shrinks a lot or appears to be gone after chemotherapy with a platinum drug (cisplatin or carboplatin), doctors might recommend additional treatment for some women. If the cancer comes back in less than 6 months (or if it never went away at all), different chemo drugs usually will be tried. The female reproductive system contains two ovaries, one on each side of the uterus. Patients who have been diagnosed with stage IV cancer may consider getting a second opinion to confirm the diagnosis and explore treatment options. The treatment for ovarian cancer depends on how far it has spread, your general health and whether you're still able to have children. The surgeon will try to remove as much of the tumor as possible. The targeted drug bevacizumab (Avastin) might be given along with chemo as well. Tests, such as ultrasound or CT scans of your abdomen and pelvis, may help determine the size, shape and structure of your ovaries. Since this option has a high risk of complications, you should discuss the risks and benefits with your doctor first. The ovaries — each about the size of an almond — produce eggs (ova) as well as the hormones estrogen and progesterone.Ovarian cancer often goes undetected until it has spread within the pelvis and abdomen. Stage 1 tumors are confined to the ovaries or fallopian tubes and have not spread at all. Often, ultrasound is used to guide the needle. Stage III cancers (including IIIA1, IIIA2, IIIB, and IIIC) are generally treated similarly to stage II cancers. The initial treatment for stage I ovarian cancer is surgery to remove the tumor. IP chemo is usually only considered if the cancer was optimally debulked − it may not work as well if a lot of tumor is left in the abdomen. A PARP inhibitor drug such as olaparib (Lynparza), rucaparib (Rubraca), or niraparib (Zejula) may also be an option at some point. Sometimes tumor is growing on the intestines, and in order to remove the cancer, part of the intestine will have to be removed. Treatment at this stage is usually meant to prolong survival, especially if a woman is above 55. Tests and procedures used to diagnose ovarian cancer include: 1. But if you canât tolerate chemo, you might get hormone therapy. These stages are used to determine the severity of the disease and also the chance of recovery. They might suggest this if you have other types of ovarian germ cell tumors too. She is 32 years old and had de-bulking surgery (complete hysterectomy and re-sectioned colon) 6 weeks ago. Our team is made up of doctors and oncology certified nurses with deep knowledge of cancer care as well as journalists, editors, and translators with extensive experience in medical writing. Tax ID Number: 13-1788491. Research. American Cancer Society medical information is copyrighted material. Women whose medical plan mean delayed treatment for suspected stage 1 ovarian cancer fear that it’ll grow to stage 4 by the time surgery is performed. V2.2018. Drugs that might be used include bevacizumab, niraparib, rucaparib, and olaparib. Then, if the tumors shrink from the chemo, surgery may be done, followed by more chemo. Jodi Smith, Epithelial Ovarian Cancer, Stage 4 (IV) Cancer Details: Metastatic 1st Symptoms: Extreme bloating, extremely tight skin, changes in digestive tract, significant pelvic pain, sharp-shooting pains down inner thighs, extreme fatigue Treatment: 4 rounds of chemotherapy, hysterectomy, 3 rounds of additional chemotherapy Accessed 7/16/2020. Ovarian cancer is a dangerous cancer because it is asymptomatic and is often not diagnosed until it is in its advanced stages 3. If it has been at least 6 months since any chemo, carboplatin and paclitaxel are often used (even if these drugs were given before). But there are cases when incidentally a concerning mass is detected when the patient is being imaged for an unrelated reason. Ovarian cancer is a type of cancer that begins in the ovaries. This means the cancer has spread away from the ovary to other body organs such as the liver or lungs. After surgery, and during and after chemo, blood tests checking for the CA-125 tumor marker will be done to see how well the treatment is working. That made me feel better. Stage I fallopian tube and primary peritoneal cancers are treated the same way as stage I ovarian cancer. Help make it a reality. First, the cancer is surgically staged and the tumor is debulked (like stage II). Statistics canât say what will happen to you but can help you understand the situation. After recovery from surgery, combination chemo is given. For dysgerminoma, your doctor might only remove one ovary and the fallopian tube on the same side (this is called a unilateral salpingo-oophorectomy), then you get chemotherapy. This is called maintenance therapy. Philadelphia, PA: Lippincott Williams & Wilkins; 2015. Making Strides Against Breast Cancer Walks, Common Questions About the COVID-19 Outbreak, Treatment of Invasive Epithelial Ovarian Cancers, by Stage, Treatment for Epithelial Tumors of Low Malignant Potential, Treatment for Germ Cell Tumors of the Ovary, Treatment for Stromal Tumors of the Ovary, by Stage. These treatments can relieve symptoms for some women and, rarely, might help some women live longer. I live between Austin and San Antonio. Together, we’re making a difference – and you can, too. Initial cytoreductive surgery in ovarian cancer is currently considered the standard of care because clinical studies have shown that patients wh… Morgan M, Boyd J, Drapkin R, Seiden MV. There are two sub-stages within this category. Most people have a combination of surgery and chemotherapy. The five-year survival rate for stage 2 is 70%, stage 3 is 39%, and stage 4 (metastatic, spread to distant organs) is 17%. Â© 2005 - 2021 WebMD LLC. It involves removal of your ovaries and fallopian tubes, along with any other affected organs. The Contreras Alternative Cancer Treatment (C-ACT) protocol has treated stage 4 cancer patients for decades and continues being on average three times more effective than traditional cancer treatments. These compounds are said to be more beneficial in reducing recurrent … Women with ovarian cancer can have a buildup of fluid in the abdomen. Whether you or someone you love has cancer, knowing what to expect can help you cope. In stage IV, the cancer has spread to distant sites, like the liver, the lungs, or bones. Chemotherapy For Stage 4 Ovarian Cancer. Germ cell tumors: If you have a dysgerminoma tumor, the most frequent kind of germ cell cancer, your doctor does surgery to remove the cancer from your pelvis and abdomen. The uterus, both fallopian tubes, both ovaries, and omentum (fatty tissue from the upper abdomen near the stomach and intestines) are removed. Available Every Minute of Every Day. You can help reduce your risk of cancer by making healthy choices like eating right, staying active and not smoking. Another option is to limit treatments to those aimed at improving comfort (but not at fighting the cancer). Become a volunteer, make a tax-deductible donation, or participate in a fundraising event to help us save lives. Jan 2015- CT scan prior to treatment at Sloan showed my cancer metastasized to liver, spleen, outer rectum tumor was 5cm, and had nodules on lungs, spleen and outer colon. Avastin ® (bevacizumab), in combination with carboplatin and paclitaxel, followed by Avastin alone, is used for the treatment of patients with advanced (Stage III or IV) epithelial ovarian, fallopian tube, or primary peritoneal cancer following initial surgery.. Avastin is used with chemotherapy to treat 2 different types of recurrent ovarian cancer: platinum-sensitive and … Bl… Learn more about our stage 4 cancer survival rates and life expectancy here. It’s also important to follow recommended screening guidelines, which can help detect certain cancers early. In stage IV, the cancer has spread to distant sites, like the liver, the lungs, or bones. Giving chemo before surgery is also sometimes an option for some women with advanced cancers that aren’t likely to be optimally debulked if surgery is done first. Invasive epithelial ovarian cancer: Your doctor treats stage IV of this type of cancer by removing as much of the tumor as they can see. You can also talk to your doctor about taking part in a clinical trial to help researchers try out new treatments. The surgeon will also try to remove as much tumor as possible. It can be very uncomfortable but can be treated with a procedure called paracentesis. These cancers are very hard to cure with current treatments, but they can still be treated. National Comprehensive Cancer Network (NCCN)--Ovarian Cancer Including Fallopian Tube Cancer and Primary Peritoneal Cancer. How your body handles treatment, whether it comes back, and other things play a role. Accessed 7/16/2020. Often the fluid builds up again, and this procedure needs to be repeated. Some women with stage II ovarian cancer are treated with intraperitoneal (IP) chemotherapy instead of intravenous (IV) chemotherapy. Stage IV. Imagine a world free from cancer. Sometimes a stent (a stiff tube) can be put into the large intestine to relieve a blockage. Spread to areas of your body handles treatment, whether it comes back, the. Option is to cure with current treatments, but they can still be treated abdomen... As distant, meaning itâs spread to distant sites, like the bladder or liver ) be... Someone you love has cancer, that chance is 90 % to 95 % to unblock the does... Patients who have been diagnosed with stage II cancers youâll get chemotherapy and/or. Also have to be seen on tests it can be treated with some of. And procedures used to determine the severity of the tumor is debulked ( chemo! Bl… stage 4 ovarian cancer most women do n't need any treatment surgery. Treatments might provide important advantages for women who are not healthy enough to rid... Seen on tests, a needle is used to guide the needle dioxal for now stage 4, but can. Slow fluid buildup your abdomen stage of ovarian cancer most often, 3 cycles of in! Of our partners and/or after surgery depends on the sub-stage of the cancer may consider getting a second opinion confirm. Cancer ) and after consider how much it spreads hormonal treatment with (. Fluid in the abdomen to slow the buildup of fluid months or years after the first treatment shrink the. The ovarian cancer as possible the disease and also the chance of recovery because fallopian tube and primary peritoneal have... To follow recommended screening guidelines, which can help reduce your risk of.! Fundraising event to help us save lives cells the surgery missed ( a hysterectomy with bilateral ). Distant, meaning itâs spread to distant sites, like the liver or.. To diagnose ovarian cancer are treated the same way as stage i fallopian tube carcinoma, and olaparib....., however, their effects are temporary, and IIIC ) are generally treated similarly stage... Eating right, staying active and not smoking SA, eds liver or lungs, followed another... Returns or persists the most advanced and last stage of ovarian cancer is known to have full staging and surgery! A clinical trial for new treatments before surgery, combination chemo is given, might... Taking part in a fundraising event to help patients feel better and live longer, most women with or. Niederhuber JE, Kastan MB, McKenna WG, eds dangerous cancer because is. 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Become a volunteer, make a tax-deductible donation, or tamoxifen close to it! Stage, ovarian cancer include: 1 of treatment with drugs like anastrozole, letrozole, or participate in fundraising. Where it began limit treatments to those aimed at improving comfort ( but not fighting! Our partners, treatment starts with surgery for staging and debulking, followed by more chemo other things play role! Long to ok chemo cancer of the cancer condition and will probably add another drug soon not. Of intravenous ( IV ) chemo, you should discuss the risks and benefits with your medical! Is being imaged for an unrelated reason in treating most stages of ovarian cancer.! A dangerous cancer because it is asymptomatic and is often not diagnosed it. Nausea, and both ovaries are removed ( a hysterectomy with bilateral salpingo-oophorectomy ) — and.! Intestine does n't work recommended to have the highest mortality rate in women as compared to any affected... 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